The Association of Coagulation Factor V (Leiden) and Factor II (Prothrombin) Mutations with Stroke

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the association of coagulation factor v (leiden) and factor ii (prothrombin) mutations with stroke

conclusions the prevalence of both fv and fii variants are population based. iran is an ethnically diverse country. therefore, for a comprehensive analysis of a potential association of fv and/or fii mutations with stroke among iranian population, epidemiological studies could be conducted among different ethnic groups. patients and methods the study population consisted of 153 patients of diff...

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The Association of Coagulation Factor V (Leiden) and Factor II (Prothrombin) Mutations With Stroke

BACKGROUND Epidemiological studies indicate that over the past forty years, the stroke incidence rates has increased. Factors V and II mutations are established genetic-variant risk factors for venous thrombosis; however, their contribution to stroke is a controversial issue. OBJECTIVES This study aimed to investigate the potential association of FV and FII mutations with stroke in an Iranian...

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The Association between Preeclampsia and Defined Polymorphisms in Prothrombin and Coagulation Factor V Genes

Background & Aims: Preeclampsia is one of the complications of pregnancy and a major cause of maternal mortality. Since, hypercoagulation is one of the risk factors, defined polymorphisms of V and II coagulation factors (G1691A and G20210A) may increase the risk of the disease. Methods: This investigation was performed on blood samp...

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Frequency of factor V Leiden (G1691A) and prothrombin (G20210A) polymorphisms in Population of Kerman Province, Iran

Background & Aims:Thromboembolism is an acute cardiovascular disease that ranges from clinically unimportant to massive embolism. Both acquired and hereditary risk factors contribute to the disease.
We aimed to determine the prevalence of two hereditary predisposing factor of the disease, prothrombin G20210A and factor V Leiden (G1691A) polymorphisms, in Kerman population.<br /...

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Factor V Leiden, MTHFR C677T and Prothrombin Gene Mutation G20210A in Iranian Patients with Venous Thrombosis

Background: Factor V Leiden, Prothrombin gene (G20210A) and MTHFR (C677T) polymorphism are the main biomarkers for evaluation of tendency for venous thromboembolism. We aimed to investigate the frequency of mutations in factor V Leiden, Prothrombin G20210A and MTHFR C677T and identify the genetic status for these mutations in patients with venous thrombosis. Methods: This study was carried out...

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ژورنال

عنوان ژورنال: Iranian Red Crescent Medical Journal

سال: 2014

ISSN: 2074-1804,2074-1812

DOI: 10.5812/ircmj.11548